It’s long been known that women’s fertility dips as they get older (and especially after they are in their mid-30s), but the traditional belief has been that males didn’t have this issue.
This may not be the case, according to a Colorado study performed in conjunction with the National Foundation for Fertility Research (NFFR) that has concluded that sperm from middle- and older-aged male mice is not as viable as that from younger male mice.
In the mice, sperm quality began to decline in their middle years, which would be roughly 40 years of age in a human man. And if the findings translate from mice to men, it could shed some light on male infertility.
For instance, a couple who is having fertility issues may find that the problem lies with the sperm quality of the man if he is in or past middle age. Should this be the case, there are options that could help the partners conceive using the strongest of his sperm as determined in a laboratory setting.
Key results of the study showed that sperm from midlife and older mice produced embryos that:
- Were less likely to implant in the woman’s uterus than were those from younger male mice.
- Were less likely to develop in the womb if they were able to implant.
If you would like to learn more about male infertility or other fertility issues, please contact the Reproductive Science Institute (RSI) to schedule a consultation.

